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Lily, a young, white teen runs away from her abusive father accompanied her black nanny, Rosaleen. She only knows she has to get to Tiburon, South Carolina, because one of the few remaining things she has from her mother is a picture of a black Madonna advertising honey. She believes that if she can get to where that honey was made, she would find someone who knew her mother. She winds up staying with three black sisters who are beekeepers, and who know how to keep secrets, too.
Aside from the bee-keeping lore sprinkled throughout the novel in the form of quotes beginning each chapter, we - and Lily and Rosaleen, and the three sisters, May, June, and August - learn much about history, mothering, and love.